Pair Name	lambda-Carrageenan Oligosaccharides, Fluorouracil
Partner Name	Fluorouracil
Disease Info	[ICD-11: 2B72.Z]	Gastric cancer		Investigative
Biological Phenomena	Induction-->Immunomodulatory
Gene Regulation	Down-regulation	Phosphorylation	AKT1	hsa207
	Down-regulation	Expression	BCL2	hsa596
	Up-regulation	Cleavage	CASP8	hsa841
	Up-regulation	Expression	PAWR	hsa5074
	Down-regulation	Expression	RELA	hsa5970
	Up-regulation	Expression	TNF	hsa7124
	Up-regulation	Expression	IFNG	hsa3458
In Vitro Model	BGC-823	Human papillomavirus-related cervical adenocarcinoma	Homo sapiens (Human)	CVCL_3360
	THP-1	Childhood acute monocytic leukemia	Homo sapiens (Human)	CVCL_0006
In Vivo Model	To generate the xenograft animal models, about 2×10⁷ BGC-823 cells in 100 μL PBS were subcutaneously injected into the left front axilla of BALB/c mice.
Result	These findings suggested that λ-COS could be used as an immune-modulating agent for chemotherapy.